Progeria, rapamycin and normal aging: recent breakthrough

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Progeria, rapamycin and normal aging: recent breakthrough

A recent discovery that rapamycin suppresses a pro-senescent phenotype in progeric cells not only suggests a non-toxic therapy for progeria but also implies its similarity with normal aging. For one, rapamycin is also known to suppress aging of regular human cells. Here I discuss four potential scenarios, comparing progeria with both normal and accelerated aging. This reveals further indication...

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ژورنال

عنوان ژورنال: Aging

سال: 2011

ISSN: 1945-4589

DOI: 10.18632/aging.100352